VP, Head of Drug Discovery

The Opportunity :

We are seeking an exceptional scientific leader to oversee our integrated Medicinal Chemistry, Computational Chemistry, Cheminformatics, and Drug Metabolism & Pharmacokinetics (DMPK) organizations. This individual will be responsible for driving the discovery and optimization of transformative small molecule therapeutics by building a highly collaborative, data-driven discovery engine that combines deep scientific expertise with modern computational approaches.

The successful candidate will be a recognized leader in small molecule drug discovery with a proven track record of advancing programs from hit identification through IND filing. They will be a key member of research leadership, fostering an environment where all disciplines work as a unified team to rapidly test hypotheses, learn from experimental data, and deliver differentiated medicines.

This role is ideal for a leader who is energized by solving complex scientific problems, embracing emerging technologies, and building high-performing scientific organizations within a fast-paced biotechnology environment.

We believe breakthrough medicines emerge from the seamless integration of human creativity, rigorous experimentation, and advanced computational science . Our discovery strategy combines hypothesis-driven biology, medicinal chemistry, computational chemistry, structural biology, and DMPK to iteratively design, test, and refine molecules based on quantitative experimental evidence. By coupling deep scientific expertise with state-of-the-art computational technologies, we aim to accelerate learning, improve decision quality, and deliver differentiated therapies for patients with serious diseases.

Your Role:

Scientific Leadership

• Lead and integrate the Medicinal Chemistry, Computational Chemistry, Cheminformatics, and DMPK organizations to create a highly effective, collaborative drug discovery engine.

• Define and execute scientific strategies that enable rapid progression from target validation to development candidate nomination.

• Champion hypothesis-driven drug discovery by integrating predictive computational methods and medicinal chemistry.

• Ensure that molecular design decisions are informed by a comprehensive understanding of